DIGST Department of Brain Sciences
|Center director||Kim Eunemail@example.com||http://home.dgist.ac.kr/ekkim/|
|Research officer||Jeon Yun-jeong(LC1)||firstname.lastname@example.org||-|
Scientific value: Although a series of candidate synapse organizers have been identified and their significance in mediating various aspects of synapse development has been established, whether and how these synapse organizers are involved in specifying key neural circuit properties across diverse brain areas remains incompletely understood. This proposal will provide novel insights into the functions of a subset of key synaptic adhesion molecules in constructing basic neural circuit wiring diagrams, contributing to building generic molecular principles of neural circuit specificity and diversity.
Medical and educational value: Numerous studies have indicated that mutations in many synaptic adhesion molecules predispose towards multiple neuropsychiatric disorders that impose enormous social and economic burdens on modern societies. Understanding how neural circuits are precisely operated at molecular and cellular levels will provide unprecedented therapeutic strategies that are based on modulating the specific synaptic adhesion signaling pathways at a set of specific neural circuits.
|Center director||Jaewon Koemail@example.com||http://jaewonkolab.org|
|Adjunct Faculty||Jiwon Umfirstname.lastname@example.org||http://umlab.org|
|Research officer||Kyung Ah Hanemail@example.com||http://jaewonkolab.org|