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Global riactice Leader's in Brain Science

Academic

  • Graduation
  • Curriculum
  • Academic Calendar
  • Lecture Schedule
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Home > Academic > Curriculum > Elective:

Curriculum

  • Requirements: for both MS and Ph.D.
  • Elective:

Electives

Applied Genetics
This class is designed to teach students having biological knowledge the practical use of genetics on their insect model studies. Especially, a Drosophila model system that is suitable for genetics approach will be the main subject of the class.
‘Fly Pushing’ is the main textbook of the class, and the related research papers will be also covered. This class will consist of lectures based on the textbook, journal presentation, and open discussion.
Behavioral Neuroscience
This lecture course focuses on behavioral neuroscience from a species- and research-based perspective. We will discuss particular but various organisms including C. elegans, Drosophila, fish, birds, and human and explore their behaviors and their contributions to neuroscience. In addition, we will learn historical and current importance of the study of animal behaviors to our knowledge of the brain and neuroscience. This lecture covers Introduction to Neuroethology, Neurobehaviors of squid, aplysia, C. elegans, drosophila, fish, birds, rodents, monkeys and human, and finally evolution of behavior.
Brain and Metabolism
The goal of this course is to understand brain metabolism. Students will learn about types, mechanisms, and regulations of metabolism in neurons and non-neuronal cells.
Text books: A. Kalsbeek et al., Hypothalamic integration of energy metabolism, Elsevier
Grade: Based on attendance and reports
Brain Pathology
This course aims to provide the in-depth mechanisms of neurological diseases, both chronic and acute. Research and up-to-date review articles inherent to the class topics will be presented by students to understand the scientific and technical approaches in the study of molecular and cellular pathogenic processes of brain diseases. This course is recommended for the students who have taken “Diseases and Disorders in Brain Science” course, indicating the prerequisite background.
Chemical Senses
“Chemical Senses” course studies the neurobiology of smell and taste in mammals and other organisms. It will focus on the anatomy and physiology of the peripheral and central nervous systems regarding smell (or olfaction) and taste (or gustation). It will also cover behavior study of the chemical senses in various models including rodents, fruit flies and nematodes. Neuronal disorders related to the chemical senses will be also examined.
Enrollment limited to 15.
Mechanisms of Cell Death
This course aims to provide the biochemical mechanisms of neuronal cell death with an overview of programmed cell death and in-depth understanding of morphological, biochemical and cell biological markers of cell death. This course is not taught with text books, but handouts which will be provided by the lecturer as powerpoint will be given. Students are required to present seminal articles in the history of programmed cell death to stimulate discussion and understanding of scientific approaches and methodologies in the field of neuronal cell death. Practical aspects of modulating cell death mechanisms for therapeutic design of neurodegenerative diseases will be covered.
Melecular Neurobiology
This course examines the biology of chemical senses in vertebrates. The focus of the course will be on the chemicals (olfaction, pheromone, and taste) and signal mechanisms. This course covers the chemical senses as the level of molecular and cellular approaches. This is an elective course for the Neuroscience major. Below there is an overview of the entire course.
Text book: Cell Biology of Olfaction (Developmental and Cell Biology Series) by Albert I. Farbman (Oct 30, 1992)
Evaluation: Based on two written exams and participations
Metabolic Diseases
The goal of this course is to understand the pathology and mechanisms of brain function in metabolic diseases especially obesity and diabetes. Students will learn about the basic research and application to prevention and treatment of metabolic diseases.
Text books: G. J. Biessels and J. a. Luchsinger, Diabetes and the brain, Humana Press
Grade: Based on attendance and reports
Mitochondrial Biology
This class is designed to teach students having biological knowledge the essential functions of mitochondria and our current understanding about the mitochondrial dysfunction in many diseases. Students will present research papers or review papers, and then all students will participate in the open discussion.
The class will cover major mitochondrial functions such as energy production, antioxidant defense, Ca2+ homeostasis, as well as the fusion/fission dynamics of mitochondria, etc.
Neurochemistry
This course is intended to introduce you to the field of neurochemistry. There are four cornerstones to modern neurochemistry: chemical composition and architecture, metabolic neurochemistry, chemistry of neural transmission, and methodologic development. About half of the course will cover the chemistry of neural transmission and a quarter will cover chemical composition and metabolism. Throughout the course, the functional aspects of all neurochemical mechanisms will be discussed. An introductory knowledge of biochemistry will be helpful in understanding the material presented. Evaluation: Based on two written exams and participations
Neurogenetics
This lecture course focuses on one of the key fields in modern neurobiology, neurogenetics, which attempts to unravel the genetic basis of brain structure, brain development and behavior. The course mostly refers to the simple model organism C. elegans but also establishes crucial links with vertebrates and Drosophila.
This lecture covers The Structure of Genes and Genomes, Gene Function (Transcription and Translation), Regulation of Gene Transcription, Epigenetics, Genetics of Embryogenesis , Genetics of Patterning in the Nervous System, Genetics of Axonal Pathfinding, Genetics of Chemosensation/Thermosensation, Genetics of Mechanosensation/Feeding, Genetic and Environmental Regulation of Dauer Development, and Genetics of Aging.
Neurophysiology
Ion channels are important functional part of modern neuroscience. The understanding of ion channel activity in excitable cells is required for the treatment of several types of neural and heart diseases. In this lecture series, the students will study the basic properties of ion channels, cell membranes and electrophysiology using the well-known book 'Ion channels of excitable membrane' written by professor Bertil Hille. Text book: Ion channels of excitable membranes, 3rd edition, Bertil Hille Students will be required to present the designated chapter and to write a report at the end of semester.
Sensory Biology
“Sensory Biology” course studies the biology of sensation in mammals and other organisms. It covers five senses such as sight (vision), hearing (audition), taste (gustation), smell (olfaction), and touch (tactioception). It will focus on anatomy, physiology, and mechanisms of sensory neurons and organs, and it will also cover the comparative studies of these neurons and organs between vertebrates and invertebrates in the term of neuroscience.
Enrollment limited to 15.
Signal Transduction
Consideration of the signal transduction mechanisms in the neuronal cell systems. Emphasis will be on the mechanisms of neurotransmitter, hormone, and drug action at synapses and the molecular basis for physiology and pathophysiology of the nervous system. The understanding of signal transduction through plasma membrane in neuronal cells is required for the treatment of several types of neural and heart diseases. In this lecture series, the students will study the basic pathways of receptor-mediated signal transduction through cell membranes. The format will be lecture, group discussion, and analysis of recent research.
Students will be required to present the designated recent papers and to write a report at the end of semester.